diff --git a/debian/changelog b/debian/changelog
index 5d2f3054..730a9352 100644
--- a/debian/changelog
+++ b/debian/changelog
@@ -1,3 +1,10 @@
+llvm-toolchain-13 (1:13.0.1-4) UNRELEASED; urgency=medium
+
+  [ John Paul Adrian Glaubitz ]
+  * Enable GRPC build dependency only on supported targets
+
+ -- John Paul Adrian Glaubitz <glaubitz@physik.fu-berlin.de>  Fri, 13 May 2022 21:04:32 +0200
+
 llvm-toolchain-13 (1:13.0.1-3) unstable; urgency=medium
 
   * Fix a typo in an header (closes: #1005195)
diff --git a/debian/control b/debian/control
index 05e4df58..0eef5673 100644
--- a/debian/control
+++ b/debian/control
@@ -24,7 +24,9 @@ Build-Depends: debhelper (>= 10.0), cmake, ninja-build,
     libpfm4-dev [linux-any], python3-setuptools, libz3-dev,
     llvm-spirv [ amd64 arm64 armel armhf mips64el mipsel ppc64el s390x ] <!stage1> | hello [!i386],
     spirv-tools [ linux-any ] | hello [ !i386],
-    libgrpc++-dev, libprotobuf-dev, protobuf-compiler, protobuf-compiler-grpc
+    libgrpc++-dev [amd64 arm64 armel armhf i386 mips64el mipsel ppc64 ppc64el powerpc s390x],
+    protobuf-compiler-grpc [amd64 arm64 armel armhf i386 mips64el mipsel ppc64 ppc64el powerpc s390x],
+    libprotobuf-dev, protobuf-compiler
 # "| hello" is for older buster/bionic distros without spirv support
 Build-Conflicts: oprofile
 Standards-Version: 4.2.1