diff --git a/hw/nvme/dif.c b/hw/nvme/dif.c
index 63c44c86ab..01b19c3373 100644
--- a/hw/nvme/dif.c
+++ b/hw/nvme/dif.c
@@ -115,7 +115,7 @@ static void nvme_dif_pract_generate_dif_crc64(NvmeNamespace *ns, uint8_t *buf,
         uint64_t crc = crc64_nvme(~0ULL, buf, ns->lbasz);
 
         if (pil) {
-            crc = crc64_nvme(crc, mbuf, pil);
+            crc = crc64_nvme(~crc, mbuf, pil);
         }
 
         dif->g64.guard = cpu_to_be64(crc);
@@ -246,7 +246,7 @@ static uint16_t nvme_dif_prchk_crc64(NvmeNamespace *ns, NvmeDifTuple *dif,
         uint64_t crc = crc64_nvme(~0ULL, buf, ns->lbasz);
 
         if (pil) {
-            crc = crc64_nvme(crc, mbuf, pil);
+            crc = crc64_nvme(~crc, mbuf, pil);
         }
 
         trace_pci_nvme_dif_prchk_guard_crc64(be64_to_cpu(dif->g64.guard), crc);